Another thing to consider is the price, customer service, safety, and many more. Most CBD Oil products come with a dropper and a recommended dosage on their product label. What’s great about them is that you don’t need to take the CBD oil directly and you can mix it with any beverage of your choice whether that be water, coffee, or juice. Luckily for you, Joy Organics is one of the best CBD oil sellers in the market that features a good variety of their concentrations. They have products with CBD per serving as low as 10 mg to bottle with 1500 mg of CBD oils at your disposal. Although it’s true that any full-spectrum CBD product can help the peripheral nervous system and help with nerve pain, the relief might be more effective if you followed the recommended dosage by your doctor.
All our CBD products have a so-called ‘batch number’ (i.e., a number assigned to a production batch that can be used to identify each individual product). Every time a batch of oil is made, a sample will be sent to an independent, third-party laboratory to be tested for cannabinoid potency. These reports are available to customers so that you can verify the quality for yourself.
Green Roads is one of the better-known CBD retailers available today. The flagship Green Roads CBD tea is simply known as “CBD Tea Chamomile Tea”. There’s 7mg of CBD in each 2g teabag, and you can buy a teabag for $5.99. Buddha Teas claims to differentiate itself from the competition using water-soluble CBD instead of CBD oil. Well, oil and water don’t mix, and most other CBD teas use oil-based CBD that won’t last in hot water.
Newer sources of CBD, which are derived from industrial hemp, containing CBD and traces of THC, are currently available. In another study performed on a panel of tumor cell lines with a variety of plant-derived cannabinoids, CBD was the most potent inhibitor of cancer cell growth, with significantly lower potency in noncancer cells. A CBD-rich Cannabis Dosage de CBD facile extract was equipotent to CBD, whereas CBG and CBC followed in the rank of potency. CBD is, together with CBG, the major nonpsychotropic cannabinoid found in Cannabis. It is the principal cannabinoid present in fiber-type Cannabis , a plant that is easily available to researchers, in contrast to the strictly controlled drug-type Cannabis varieties.
The American Academy of Pediatrics holds a similar stance, although it acknowledges it may provide an option for children with life-limiting or severely debilitating conditions when current therapies are inadequate. It is important to note that medical cannabis has its own significant side effects . In medical applications, THC is typically used to relieve pain, nausea, insomnia, and poor appetite. THC is a partial agonist of the CB1 and CB2 receptors.4 It produces the high, which is why it is included in so many recreational marijuana products.
Delta 8 THC interacts with the human endocannabinoid system similarly to delta 9 THC. By engaging with the ECS, delta 8 THC can help regulate nausea and vomiting, ease stress, reduce pain and inflammation, boost CBD + THC Gummies appetite, and protect neurons in the brain against damage. Therefore, only individuals living in the states with legalized marijuana for recreational use can legally purchase delta 9 THC-infused products. If you live in a place with zero legal access to cannabis, your best bet for getting cannabinoids into your system legally is purchasing full-spectrum hemp products. Delta 8 is being utilized for its therapeutic value rather than the psychotropic effects it offers.
You can be assured that your CBDfx CBD product is free from all pesticides, heavy metals, and other harmful chemicals often found in products from less reputable CBD brands. Vaping CBD is the fastest way to experience its effects (THC, too!). This is because the CBD and THC are absorbed into the bloodstream through the lungs, which happens much quicker than if you were to enjoy a CBD edible or even a sublingual CBD tincture oil. When you vape CBD and THC, you can potentially feel the effects in just a few minutes, depending on bioavailability factors, such as weight, height, body mass, tolerance, and metabolism.
With hemp extract, our CBD products contain the same health benefits of the hemp cannabis plant. Applied Cannabis Research is conducting an observational study through CA Clinics, investigating medicinal cannabis for the treatment of endometriosis. The study aims to recruit 200 women — who will be followed up for 12 months — and will collect safety and efficacy data, as well as track pain and quality-of-life outcomes. The observational study is a sub-study of the CA Clinics Observational Study , which aims to collect data on medicinal cannabis for a range of hard-to-treat conditions.
Making sure you know your dosage and properly use the product can help control your high. If you aren’t sure how it will affect you, starting with a low dosage and giving it time to work is super important. Once you know what your low bar for dosing is and how your body reacts, then you can start working your way up in small increments from there.
What Is Cbd & Cbd Oil Benefits? The Ultimate Guide
The research was funded by TheDrug.Store who had no role in any aspect of the study, including the design, data analysis, or manuscript preparation. CH is funded by a University College Hospital National Institute of Health Research Biomedical Research Centre bridging fellowship. Corroon et al. found a more even distribution between various application methods with the most popular being sublingual CBD (23% vs 72,6% in our study sample).
Regardless of the way brands advertise, CBD marketing requires a constant eye to policies and regulation changes. Brands typically work with lawyers to vet if their creative work, making sure it is compliant with the various policies. They also typically use in-house creative teams — sometimes coupled with agencies — to make sure they can change creative quickly and easily to fit with the platform policies. Educating consumers about CBD can be hard to do with digital creative, given the limitations. That’s why some brands are looking to influencers as well as audio advertising to get testimonials about the products out there. Hath is spending money podcasts while Koi has employed radio ads in Southern California.
Most users love the improved appetite, reduced pain and inflammation, and better sleep after using these tinctures. 3Chi products contain various blends of compounds, they include specific lines of products infused with specific major and minor cannabinoids, including CBD, CBN, CBG, CBC, THCV, and Delta-8 THC. 3Chi is a brand that was founded by a biochemist who had 15 years of product formulation experience. After he witnessed the healing powers of the hemp plant, he decided to help other people that had the same problem.
Unlike Δ9-THC, CBD is not a direct ligand for CB1 or CB2 receptors. Depending on the interaction, CBD can have both enhance and inhibit signaling. CBD increases serotonergic activity via enhanced 5-HT1a signaling. It also has a facilitatory effect on α3 and α1 glycine receptors, transient receptor potential of ankyrin type 1 channel and can both enhance and inhibit intracellular calcium flux. At higher concentrations CBD can activate TRPV1 and TRPV2 channels. It reduces signaling at the putative but poorly characterized cannabinoid receptor GPR55.
Please also stay aware of the emerging politics surrounding CBD in order to maintain its accessibility and to make sure your practice does not suffer from any legal ramifications. The medical benefits of Cannabis were probably first recorded around 2900 BC in the Chinese Medicine tradition. Historically, the plant has been a part of many cultures and nations, including the Jewish tradition, ancient Egypt, the Greek medical tradition, India, and Persia.
Although antidepressants may not cure depression, they can reduce the symptoms. Many types of antidepressant medications are available to treat depression, including selective serotonin reuptake inhibitors , serotonin and norepinephrine reuptake inhibitors… Include pain management, social anxiety relief, alleviating cancer-related symptoms, and neuroprotection. CBD is also believed to help enhance cardiovascular health and reduce acne growth.
Budderweeds uses ingredients grown to organic standards using natural farming methods; no chemical pesticides, herbicides, fungicides, GMOs, or artificial fertilizers come in contact with their ingredients. Additionally, Budderweeds’ products are potent, vegan, and gluten-free, while the site is wonderfully designed with user experience front and center. Dani Pepper arguably brought CBD into the mainstream with their CBD Lube . Since then they’ve developed high quality gummies, topicals, and CBD oils.
Insurance Coverage Of Cbd
We need to study pure CBD separate from pure THC, without the confounding unknown effects of other molecules present. At this time, however, clinical trials of THC in individuals under the age of 20 are probably unwise. CBD is derived from hemp, which is a plant “of the genus cannabis,” as is marijuana.
To sleep better, many of us turn to pharmaceuticals or over-the-counter drugs, but these can then cause their own problems, such as addiction or bowel irritability. In the United States, cannabidiol products generated sales of roughly five billion U.S. dollars in 2020. By 2025, CBD product sales are predicted to reach nearly 17 billion U.S. dollars in the United States.
If you’re a patient in California, click here to order 1-hour cannabis delivery online from the state’s most reliable dispensaries. Choose from thousands of products, including cannabis oils and CBD-only items. While the terms “CBD oil” and “weed oil” are often used interchangeably, the differences between the two are important to wrap your head around.
According to Oxford medicine, neuropathic pain is a form of chronic pain that is debilitating and it’s very difficult and costly to treat. But aside from directly affecting nerve pain, CBD is known to have strong anti-inflammatory and antioxidative properties. Of course, this isn’t the only study that confirms this as other studies regarding CBD show that it does have the potential of CBD as an anti-inflammatory drug. So CBD is good for pains in general even if they have no role in potentiating your glycine receptors. According to the Food and Drug Administration (FDA), the farm bill of 2018 has changed a lot of things regarding agricultural development.
CBD oil is usually ingested in drops, tinctures, and capsules, or added to foods and beverages, such as gummy candies and coffee. On the basis of distribution channel, the CBD oil extract market is segmented into B2B, and B2C. B2C has been further segmented into hospital pharmacies, online and retail stores. This report covers the current scenario and growth prospects of Global CBD Oil Extract Market for the period 2022 to 2029.
The main similarity in terms of benefits between kava and CBD is their powerful relaxing effects. This makes both supplements a great option for supporting sleep, chronic stress, anxiety, and other conditions involving excess mental stimulation. I need to note that one of the kavalactones does work through the endocannabinoid system — but instead of acting like CBD, it works more similarly to THC — the psychoactive component of marijuana plants. This is part of what makes kava a euphoric and provides mild psychoactive effects in high doses. Kava refers to the root of the Piper methysticum plant, while CBD refers to a non-psychoactive extract from the cannabis plant . While there’s no direct connection between either of these two plants, they share a lot of the same benefits towards anxiety, sleep, muscle tension, chronic pain, and more.
The product contains similar ingredients but with mango puree, cold-pressed pineapple juice, and organic apple juice. Other flavors include Cherry-Lime CBD kombucha, blueberry, and hibiscus watermelon, among others. Aqua ViTea claims that “the full flavors of chai and chaga…drift to the forefront of the formula”, while the chaga mushrooms are linked with “anti-inflammatory and anti-microbial effects”.
As CBD does not naturally dissolve in water, there is a certain amount of complexity involved with making it a suitable match for drinks. With this being the case, the effectiveness of a chosen drink will depend heavily on the type of drink selected, as well as the person involved. Overall the severity of acne can vary greatly from person to person.
In particular, high tech vaporizers can deliver marijuana extracts that are both remarkably pure and dose specific. Cannabis-derived CBD oil is found only in states with recreational or medical cannabis laws. Cannabis-type oils, in particular, are loaded with beneficial compounds that can work with the body’s endocannabinoid system to help restore well-being.
Despite fairly high awareness, only 24% of respondents said they’ve used a CBD product; 70% said they have not. Men were significantly more likely to try CBD than women, at 31% compared to only 16% of women. Adults between the ages of 25 and 34, followed by Lilliana those ages 35-44, reported the highest usage levels, at 39% and 31% respectively. The important difference is that marijuana contains a high level of the mood-altering substance THC, while hemp contains more beneficial CBD and only trace amounts of THC.
Cannabis is still illegal at the federal level, and due to its classification as a Schedule 1 drug the amount of research that can be conducted on it is limited. This is simply an acknowledgement of popular types of products in states where cannabis is legal in some form. The market is driven by the growing millennial population in key cannabis markets and increasing number of new product launches. The healthcare institute cites a lack of both evidence and FDA approval, but supports medications derived from cannabis.
Prescribing unlicensed products is often referred to as “off-licence”. Synthetically obtained cannabinoids are also considered to be novel. It is also worth keeping in mind that the Home Office is closely monitoring CBD CBD + THC Gummies products and whether the Misuse of Drugs Regulations’ definition of “exempted product” is met in each case. Other regulatory issues may arise where CBD is used in cosmetics or vaping products, where EU Directives apply.
CBD is also currently under investigation for its potential to help people with other neurodegenerative conditions like Amyotrophic Lateral Sclerosis . Animal research also suggests that CBD could protect the brain from the effects of stroke and reduced blood flow if the results can be repeated in humans. In cell studies, it was a stronger antioxidant than vitamin C or vitamin E (α-tocopherol) . Some other research suggests that CBD could protect brain cells from damage.
All these interactions seem promising when it comes to easing withdrawal symptoms and reducing the risk of addiction. Still, there’s one more thing we’d like to cover before we move on to the benefits of CBD for addicted individuals. Similarly, CBD interacts with TRPV1 receptors by binding to their sites and blocking pain signals. CBD may also impact the nuclear receptor PPAR-gamma, which regulates the storage of fatty acids on top of glucose metabolism. This way, the ECS can effectively maintain homeostasis throughout the body — a state of chemical equilibrium. When the brain interacts with substances like caffeine, nicotine, or a drug like amphetamine, this interaction causes a surge of euphoric sensations.
Scientifically, depression has often been linked to low serotonin levels. While CBD does not necessarily boost or raise serotonin levels, it could have an effect on the brain’s chemical receptors. Many prescriptions designed for anxiety sufferers often come with the possibility of dementia or other psychological impairments in the future. CBD functions in a definitively different manner from more common treatment methods.
Research investigating the effects of CBD on symptoms of anxiety and depression is ongoing. Several other studies have found that CBD may be effective for those with social anxiety and other anxiety-related disorders . Read on to discover more about CBD ointments, such as their effectiveness and a list of products to consider.
Our portfolio company Kannaway joins the board of hemp industry… You can also use cannabis extracts without a dab rig by using specially equipped vape pens and portable electronic dab rigs. These battery powered vaporizers convert the battery’s electric power into heat via its atomizer or electronic nail to convert your extracts into vapor. Electronic dab rigs tend to be larger units, about the size of a 20 oz bottle of soda. Wax vape pens are smaller units that can slide into your pocket, so you can use your cannabis extracts discreetly on the go.
Below, we’ve tried to break down some of the important factors to consider when picking which CBD hemp flower strains are right for you. While some full-spectrum CBD products contain trace amounts (no more than .3%) Buy Delta 10 Gummies Here of THC, they do not produce a psychoactive high. Lastly, it’s important to remember to never apply a CBD topical to an open cut or wound. This can cause infection and potentially lead to adverse CBD reactions.
How Do You Use Cbd Oil?
In broad spectrum CBD, the trace amounts of the delta-9 THC cannabinoid have been filtered out, along with some of the other hemp compounds. When you buy a CBD or delta-9 product with the CBDfx label, you can be assured that you’re getting a highly rated, quality CBD product. Our CBD oil is derived exclusively from cannabis hemp plants grown organically at our state-of-the-art US partner farms, and extracted with clean carbon dioxide. All of our CBD and THC products — including CBD + THC Delta-9 Vape Pens — are quality tested by an independent, third-party laboratory.
Understandably, CBD North is well known for researching the various benefits of CBD to develop natural and effective products for the masses. These products further undergo third-party lab tests, ensuring that all the ingredients meet the demands of modern healthcare. CBD North believes in the mission that every Canadian has the right to quality healthcare. Therefore, the brand has been working tirelessly to develop affordable, fair, and organic CBD products suitable for people suffering from numerous ailments. Arthritis is a long-term problem suffered by many older people, although it is sometimes a problem for younger people too.
This much I do know – marijuana laws may be changing around us but Idaho will not likely move soon toward legalizing CBD or any other marijuana product. Recall the harsh penalties for the possession of marijuana in Idaho. Until our state laws change, the safest bet to avoid potential criminal charges is to avoid messing with marijuana products, including CBD. Internet CBD sales do not likely violate federal law , but our state laws still pose a trap that could lead to criminal charges. Consumers are also becoming receptive towards the usage of cannabis plant compounds in various health and therapeutic products. Most of the users tout the extraordinary benefits of CBD in treating chronic pain and inflammation.
In the case of CBD, metabolization in the gastrointestinal tract and liver leads to loss of potency. The results we found are a must-read for anyone who wants to maximize the benefits that CBD oil has to offer. In such a scenario, the anticoagulant effects of CBD will thin the blood, which could be dangerous. According to research papers and journals, full-spectrum CBD oil is more refined and helps cure ailments faster than CBD isolate.
CBD is often referred to as non-psychoactive, but it is indeed because it can affect mood and relieve anxiety. However, it is not psychoactive in the way most people think of, in the sense that it does not cause intoxication or the feeling of being high. Most importantly, vaporizing technology helps patients take advantage of the “entourage effect” as the cannabinoids, terpenes, and other synergistic compounds in marijuana are preserved through vaping.
Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects.Psychopharmacology . Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex.Epilepsia. Interactions between cannabidiol and commonly used antiepileptic drugs.Epilepsia. CBD Pain Cream Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients.Neuropsychopharmacology. Acute effects of a single, oral dose of d9-tetrahydrocannabinol and cannabidiol administration in healthy volunteers.Curr Pharm Des.
The root cause of fibromyalgia is still poorly understood by the scientific world. Fibromyalgia causes chronic, widespread pain, along with several other symptoms affecting a patient’s physical and mental health. NuLeaf Naturals’ products are all organic, lab-tested, and optimally dosed. The hemp is sourced only from licensed organic farms in Colorado to ensure its high-quality control. Dentists should draw upon their professional judgment in advising patients who are heavy drinkers to cut back, or the users of illegal drugs to stop. Historically, cannabis has been smoked as marijuana, but is increasingly available in other forms, including edible and topically applied products.
Forms Of Cbd Include:
However, we have provided a list of links at the end of this post to articles that provide much more in-depth information on the topic of CBD’s benefits. If you don’t know the answers to these questions, you might want to check these posts out before you delve into the science behind the effects of CBD on the human body. CBD products come in a myriad of different formulas intended to produce various distinct effects. What this means is that choosing the wrong CBD product can end up causing you more harm than good. Determining which CBD oil product is ideal for your needs requires that you do some homework. The North American market for legal cannabis should reach $25.5 billion by 2023 from $10.7 billion in 2018 at a compound annual growth rate of 18.9% for the period 2018 to 2023.
When medical marijuana is either smoked, vaped, eaten or applied topically as a cream, science indicates that substantial pain relief can be achieved. The topical application is of particular interest to seniors, some of whom may be uninterested in the psychoactive effects of cannabis and only want pain relief. It also means a stark increase in the number of people suffering from age-related illnesses and other conditions.
The inventory of Pure CBD Softgels 300mg is restricted on the official website of this manufacturer. This CBD product is made from the CO2 extraction method and it does not contain THC in any amount. Best CBD gummies for anxiety, CBD gummies where to buy, Cannabis gummies, CBD effects review.
Unlike THC, CBD won’t get you “high”, but is has shown promise in animal research for the treatment of anxiety, pain, inflammation, cancer, and more. A reputable company will always back their claims with lab reports and clearly state the ingredients of their products. You can always refer the reviews and rating shared by other users, based on which you can make your purchase decision. There are occasional reports of somnolence and sedation have been occasionally reported with CBD use. These side effects may diminish over time and are more likely to be reported earlier in treatment.
Dr Parmaris a double board-certified adult and child psychiatrist with Community Psychiatry based in Newark CA. She earned her medical degree at Terna Medical College & Hospital in Mumbai, India. While interest grows in cannabis, the medical community is eager for more research on how it might affect autism. In the United States, tight controls and a lack of adequate funding limits how cannabis is studied. The CBD Industry Database currently has over 12,000 CBD companies consisting of retailers, wholesalers and manufacturers. As well as receiving a master database, you will also receive a folder with individual files for every country. This is useful if you would like to geo-target your B2B marketing campaigns.
While still a relatively small factor in consumer markets, CBD penetration is growing. In 2019, CBD accounted for four percent of the global vitamin and dietary supplements market. Data Bridge Market Researchset forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. The impact of marijuana use on glucose, insulin, and insulin resistance among US adults.
Frequently Asked Questions Faqs About Cbd
The usual CBD formulation is oil, but CBD is also sold as an extract, a vaporized liquid and an oil-based capsule. Food, drinks and beauty products are among the How many CBD gummies should I eat? many CBD-infused products available online. There are many different brands of CBD oil out there, which can make it confusing to find one that’s right for you.
In patients with paediatric-onset drug-resistant epilepsy, CBD products reduced seizure frequency by 50 per cent or more in up to half of the patients and achieved seizure freedom in a small number of patients. Several studies have reported improved quality of life in paediatric Kann man von CBD besser schlafen? and adult groups, but overall there are few studies of how effective CBD is in treating adult epilepsy. There is not enough evidence to recommend this treatment for adults. The commercialization of products with cannabidiol has undergone a significant increase.
Cannabidiol Oil Market Research Report By Product, By Source, By Distribution Channel, By Application, By Region
Little to no effect was reported in those who took the placebo, a 150-mg dose of CBD, or a 600-mg dose of CBD . Some research suggests that CBD may be effective for certain types of pain, including nerve pain and back pain, when used on its own. Studies have shown that CBD may help reduce chronic pain by affecting endocannabinoid receptor activity, reducing inflammation, and interacting with neurotransmitters . More recently, scientists have discovered that certain components of cannabis, including CBD, are responsible for its pain-relieving effects. For now, people should ask a healthcare professional for advice about which product to use and how much to take.
Another study shows that the potentiation of your glycine receptors can lead to cannabis-induced analgesia which opens up the therapeutic effects of the cannabis plant especially when it comes to the nerves. Aside from concentration variety, Joy Organics also has a good product variety when it comes to the cannabis plant. So you’ll have tons of choices to choose from starting from CBD oil to even CBD gummies.
Smoking cannabis has been shown in repeated studies to lower intraocular pressure for three to four hours. Eye drops containing THC and CBD have been tried but the dosages involved aren’t high enough to reduce IOP adequately. Seniors find the camaraderie of traveling to dispensaries and shopping together to be an excellent way to socialize and get the medical cannabis they need. As NPR points in a recent article, seniors find the camaraderie of traveling to dispensaries and shopping together to be an excellent way to socialize and get the medical cannabis they need. There is a lot of information about cannabis available online, but for many, it’s difficult to determine what’s factual and what isn’t. Having a community of cannabis-using peers to bounce ideas off of, as well as frequent guest experts to field questions can be a critical component of many seniors’ knowledge base and support network.
Occasional side effects of CBD include nausea, fatigue, and irritability. However, it can increase the level of the blood thinner coumadin and interfere with some medications, like grapefruit juice does. So if you are on other medications, be sure to consult with your medical care provider before taking CBD. Sleep can become even more challenging as we age, but it’s no less important. Not only does a good night’s sleep help us feel more energetic the next day, it’s essential for maintaining brain health. As a natural remedy with few side effects, CBD is typically safer than doctor-prescribed or over-the-counter medications, too.
As a result, kava is exclusive to the equatorial islands in the pacific ocean — such as Vanuatu, Fiji, Hawaii, Papua New Guinea, The Solomon Islands, and Tonga — to name a few. All six of these primary kavalactones have a direct impact on neurotransmitter function in the brain. The whole root is traditionally used as medicine and for social or ceremonial purposes. Everything from our blood pressure to hormone levels needs to be kept within a specific range of values. This may sound strange and unnecessary, but it’s actually very important for different organs of the body to work in unison together. In basic terms, the endocannabinoid system acts as a messaging system for the body — it works like an instant messaging service for the organs of the body.
Instead, some research suggests that it may naturally protect against the marijuana high . Its proponents claim that it is a safe anti-inflammatory that can improve conditions like irritable bowel disease, schizophrenia, anxiety and help you get more sleep. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed.
Sublingual ingestion of CBD involves placing CBD oil directly under the tongue. While ease of dosage and a faster uptake time are key benefits provided through this method, there are also other considerations. Sublingual consumption also allows for faster absorption since the digestive system is removed from the process. Each license type allows a set number of users to access the report. The risk of FDA and FTC enforcement of CBD products has been tied to claims to treat serious medical conditions. The agencies also have focused their attention on products that target vulnerable populations (e.g., infants and children).
While some individuals with pain have reported that their use of opioids has been reduced when they also use medicinal cannabis, clinical studies in this area are still ongoing. Despite the myriad of health benefits that hemp oil offers to the human body, manufacturers and distributors are still facing hurdles due to the restrictions imposed by regulatory bodies all over the world. The FDA is still in the process to fully study the true potential of this cannabis extract. Despite the bans on the distribution of various marijuana drugs, entrepreneurs are still experimenting to come up with new compounds made from this miraculous substance.
Left untreated the disorder can continue into adolescence and then into adulthood. In Japan it has been reported that there are a million teenagers with SAD who may withdraw into their living spaces for up to six months at a time. Professor Masataka is highly encouraged by the results of his trial of CBD in teenagers with SAD. Professor Masataka recommends a further clinical trial of robust design, which compares treatment of SAD with CBD and the most commonly used pharmacological treatment option.